Drafted by the New York Islanders in the 2004 NHL Entry Draft, Campoli swiftly ascended to the professional ranks. His rookie NHL season in 2005–06 saw him make an immediate impact, showcasing his offensive prowess with nine goals and twenty-five assists. Throughout his NHL career, Campoli demonstrated versatility and resilience, donning jerseys for the Ottawa Senators, Chicago Blackhawks, New York Islanders, and Montreal Canadiens.